Can gut microbiome foods help combat severe malnutrition?

Recent research suggests that stimulating the gut microbiome may play a crucial role in treating severe malnutrition in children. A study conducted in Bangladesh by Jeffrey Gordon of Washington University and Tahmeed Ahmed of the International Center for Diarrheal Disease Research focused on children aged 12 to 18 months. These children, who suffered from severe malnutrition, were treated with a supplement designed to nourish their gut microbiome. The supplement contained ingredients such as chickpea, banana and peanut flour, which promote the growth of beneficial gut bacteria.

Study methodology and findings

The study This involved 124 children who had been admitted to hospitals due to severe malnutrition. After receiving treatment to tackle any infections, they were divided into two groups: one was given the microbiome-targeted supplement, while the other was given traditional ready-to-eat therapeutic foods (RUFs). The findings showed that those given the microbiome supplement gained weight faster and showed improved levels of proteins essential for the development of their muscles, bones and brain.

Impact on intestinal health

Previous studies found that malnourished children had an underdeveloped gut microbiome, lacking the variety of beneficial bacteria found in healthy children. By administering targeted nutritional supplements, researchers hope to restore balance to the gut microbiome, which is crucial for overall health and development.

Significance of the study

The implications of this research are significant. If this microbiome-targeted approach proves effective on a larger scale, it could revolutionize the treatment of malnutrition, not only addressing immediate nutritional needs but also promoting long-term health benefits. The World Health Organization has launched a multi-country trial to assess the effectiveness of these supplements in different cultural and dietary contexts. This innovative approach could provide a sustainable solution to malnutrition, potentially benefiting millions of children around the world.