Just not this week. The Bengals (3-2) are likely to run back without Samaje Perine after he tested positive for coronavirus this week, putting more strain on Joe Mixon, who is already third in attempts and battling an ankle injury. Even with an improved offensive line protecting Joe Burrow and the rise of Ja’Marr Chase as the front-runner for offensive rookie of the year, Cincinnati could struggle to defend against a Lions defense playing for pride. Choose: Lions +3
Los Angeles Rams at Giants, 1:00 p.m., Fox
Line: Rams -10.5 | Total: 47.5
With quarterback Daniel Jones (concussion) out and a long list of injuries hampering the entire receivers corps and Saquon Barkley running back, the Giants (1-4) will try to rush back anyone who can catch a ball from backup Mike Glennon. The Rams (4-1) may look a little shocked with the early East Coast start, but this one needs to be decided soon. Choose: Rams -10.5
Kansas City at Washington Footballers, 1:00 p.m., CBS
Line: Kansas City -6.5 | Total: 55.5
Kansas City’s offense had to be mind-bogglingly efficient to even compete this season so far, and the three losses have followed a common script: opponents who can limit Tyreek Hill to fewer than 100 receiving yards and aggressive play calls against the defense of Kansas City. Kansas City can convert, can come with a win.
The Ravens, Chargers and Bills wrote the blueprint, but Washington (2-3) is unlikely to execute it well. His defense has enabled the league’s fifth most passing yards (1,467) and has just nine sacks in six games, despite Chase Young-Montez Sweat’s defensive line combination. Mahomes, whose six interceptions rank third in the NFL, has shown he can quickly find receivers with his kick pass and Hill gives him a deep target against a less talented secondary. Kansas City (2-3) should get a confidence boost. Choose: Kansas City -6.5
Houston Texans in Indianapolis Colts, 1:00 p.m., CBS
Line: Foals -9.5 | Total: 43
How does a team recover from a 19-point lead? Playing the Texans (1-4) is a start.
Before the Colts (1-4) allowed Ravens quarterback Lamar Jackson from behind on “Monday Night Football,” they looked shockingly efficient on both sides of the ball. upon surrender their second half lead to the Patriots last week, the Texans wasted rookie Davis Mills’ best game (312 yards and three touchdowns). Carson Wentz has more experience and works with a better all-round roster. The Colts should be covering at home. Choose: Foals -9.5
Las Vegas Raiders at Denver Broncos, 4.25 pm, CBS
Line: Broncos -3.5 | Total: 44
Following the resignation of Jon Gruden Monday night, the Raiders (3-2) must prepare for an infernal Broncos defense under interim coach Rich Bisaccia. Losers of two straight, the Broncos (3-2), will pounce on a Las Vegas team facing organizational turmoil and shuffling offensive linemen, including shifting first-round draft pick Alex Leatherwood from tackle to guard, due to injuries . Choose: Broncos -3.5