Research shows a popular diet shot is more effective in women, with some losing a quarter of their body weight
A drug once dubbed the “King Kong” of diet pills helps women lose significantly more weight than men, research shows.
Analysis shows that women lost up to a quarter of their body weight by using Mounjaro for up to 20 months.
In men, this percentage is 18 percent, according to studies involving more than 4,500 obese adults.
According to experts, the reason for the variation is not yet known. According to them, the results show that it is an effective means to combat obesity in both sexes.
The weekly shot belongs to a class of drugs called GLP-1 agonists, which mimic a hormone that suppresses appetite, reducing food intake.
The weekly injection is in a class of drugs called GLP-1 agonists, which mimic a hormone that helps suppress appetite and thus reduce food consumption.
Analysis shows that women lost up to a quarter of their body weight by using Mounjaro for up to 20 months
Research has also shown that the drug tirzepatide increases the production of insulin. Insulin is the hormone that regulates blood sugar levels and is essential for fighting type 2 diabetes.
It was provisionally approved earlier this year by UK regulators for people with a BMI of 35 or more and at least one weight-related comorbidity, such as heart disease or type 2 diabetes.
Researchers at Eli Lilly analyzed the results of four of their studies, in which 4,677 obese adults took the drug for up to 88 weeks.
In all studies, tirzepatide was associated with significant weight loss compared with placebo groups.
According to the findings, presented at the European Association for the Study of Diabetes (EASD) in Madrid, men and women were able to achieve similar goals of five, 10 and 15 percent weight loss.
But the effects were more substantial in women, with weight loss ranging from 11.5 to 27.6 percent of their total body weight, compared with between 8.8 and 18.9 percent in men.
Presenting the findings, Dr Luis-Emilio García-Pérez said more research is needed to understand why women lose more weight.
He said, ‘I don’t have an explanation for it right now. It could be related to body fat distribution, it could be related to pharmacology, but we don’t have an answer yet.’
He added: ‘The safety profile was largely similar across genders, but a numerically higher incidence of nausea and vomiting was observed in women.’
